Publications

2023

Feng, Bing, et al. “Post-hospitalization rehabilitation alleviates long-term immune repertoire alteration in COVID-19 convalescent patients.” Cell Proliferation, March 2023, doi: 10.1111/cpr.13450

Tang, Wai Kwan, et al. “A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.” Immunity, vol. 56, Feb. 2023, p. 433-443.E5, doi: https://doi.org/10.1016/j.immuni.2023.01.012

Martinez, Ryan J., et al. “Type III interferon drives thymic B cell activation and regulatory T cell generation.” PNAS, vol. 120, Feb. 2023, doi: https://doi.org/10.1073/pnas.2220120120

2022

Jia, C. et al. “Immune Repertoire Sequencing Reveals an Abnormal Adaptive Immune System in COVID-19 Survivors.” Journal of Medical Virology, November 2022. doi:10.1002/jmv.28340.

Duurland CL, et al. “CD161 Expression and Regulation Defines Rapidly Responding Effector CD4+ T Cells Associated with Improved Survival in HPV16-Associated Tumors.Journal for ImmunoTherapy of Cancer, vol. 10, Jan. 2022. doi: 10.1136/jitc-2021-003995.

Husain-Krautter, Sehba, et al. “Skewing of the Antibody Repertoire in Cerebrospinal Fluid B Cells from Healthy Controls and Patients with Schizophrenia.Behavioural Brain Research, vol. 422, Mar. 2022, doi:10.1016/j.bbr.2022.113743.

Kumar, Deepak, et al. “T-follicular Helper Cell Expansion and Chronic T-Cell Activation are Characteristic Immune Anomalies in Evans Syndrome.Blood, vol. 139, no. 3, Jan. 2022, p. 369-383, doi:10.1182.blood.2021012924.

Liu, Mingyong, et al. “Circulating Tregs accumulate in omental tumors and acquire adipose-resident features.” Journal for ImmunoTherapy of Cancer, Mar. 2022, doi:10.1158/2326-6066.CIR-21-0880.

Xia, Miaoran, et al. “Next-Generation Sequencing Revealed a Distinct Immunoglobulin Repertoire with Specific Mutation Hotspots in Acute Myeloid Leukemia.Biology, vol. 11, no. 2, Jan. 2022, p. 161, doi: 10.3390/biology11020161.

Song, Cailing, et al. “Immune repertoire analysis of normal Chinese donors at different ages. Cell Proliferation, Aug. 2022, doi: 10.1111/cpr.13311.

Peng, Jiao, et al. “DNA-Programmed Orientation-Ordered Multivalent Microfluidic Interface for Liquid Biopsy.Analytical Chemistry, Jun. 2022, doi: 10.1021/acs.analchem.2c01359.

Guo, Fei, et al. “Distinct Injury Responsive Regulatory T Cells Identified by Multi-Dimensional Phenotyping.Frontiers in Immunology, May 2022, doi: 10.3389/fimmu.2022.833100.

Zhou, Changping, et al. “Meningeal lymphatics regulate radiotherapy efficacy through modulating anti-tumor immunity.Cell Research, vol. 32. Mar. 2022, 543-554, doi: 10.1038/s41422-022-00639-5.

Cook, Katherine Wendy, et al. “Vaccine Can Induce CD4-Mediated Responses to Homocitrullinated Peptides via Multiple HLA-types and Confer Anti-Tumor Immunity.Frontiers in Immunology, Apr. 2022, doi: 10.3389/fimmu.2.

Zhang, Yudi, et al. “Analysis of B Cell Receptor Repertoires Reveals Key Signatures of the Systemic B Cell Response after SARS-CoV-2 Infection.Journal of Virology, vol. 96, no.4, Feb. 2022, doi: 10.1128/jvi.01600-21.

Chou, Chun, etal. “Programme of self-reactive innate-like T cell-mediated cancer immunity.Nature, vol. 605, Apr. 2022, p. 139-145, doi: 10.1038/s41586-022-04632-1.

Chen, Yi-Tung, et al. “Longitudinal High-Throughput Sequencing of the T-Cell Receptor Repertoire Reveals Dynamic Change and Prognostic Significance of Peripheral Blood TCR Diversity in Metastatic Colorectal Cancer During Chemotherapy.Frontiers in immunology, Jan. 2022. doi: 10.3389/fimmu.2021.743448.

Hong, Hyebeen, et al. “Postnatal regulation of B-1a cell development and survival by the CIC-PER2-BHLHE41 axis.Cell Reports, vol. 38, no. 7, Feb. 2022, doi: 10.1016/j.celrep.2022.110386.

Delmonte, Ottavia M., et al. “Poor T-cell receptor β repertoire diversity early posttransplant for severe combined immunodeficiency predicts failure of immune reconstitution.Journal of Allergy and Clinical Immunology, vol. 149, no.3, Mar. 2022, p. 1113-1119, doi: 10.1016/j.jaci.2021.07.029.

Kumar, Deepak, et al. “T-follicular helper cell expansion and chronic T-cell activation are characteristic immune anomalies in Evans syndrome.Blood, The Journal of the American Society of Hematology, vol. 139, no. 3, Jan. 2022, p. 369-383, doi: 10.1182/blood.2021012924.

2021

Borstel, A. von et al. “Repeated Plasmodium falciparum infection in humans drives the clonal expansion of an  adaptive γδ T cell repertoire.Science Translational Medicine, vol. 13. Dec. 2021, doi: 10.1126/scitranslmed.abe7430.

Al Khabouri, Shaima, et al. “TCRβ Sequencing Reveals Spatial and Temporal Evolution of Clonal CD4 T Cell Responses in a Breach of Tolerance Model of Inflammatory Arthritis.” Frontiers in Immunology, vol. 12, Apr. 2021, doi:10.3389/fimmu.2021.669856.

DiMuzio, Jillian, et al. “Unbiased Interrogation of Memory B Cells from Convalescent COVID-19 Patients Reveals a Broad Antiviral Humoral Response Targeting SARS-CoV-2 Antigens Beyond the Spike Protein.Vaccine: X, vol. 8, Aug. 2021, doi:10.1016/j.jvacx.2021.100098.

FitzPatrick, M, et al.“O43 The Phenotype and TCR Repertoire of Intestinal CD8+ T cells is Altered in Coeliac Disease.Gut, vol. 70, Jan.2021, p. A24. doi: 10.1136/gutjnl-2020-bsgcampus.43.

Lee, Linda, et al. “A Comparison of Ex Vivo Expanded Human Regulatory T Cells Using Allogeneic Stimulated B Cells or Monocyte-Derived Dendritic Cells.Frontiers in Immunology, Jun. 2021, doi: 10.3389/fimmu.2021.679675.

Li, Ye, et al. “Diversity of Dominant Peripheral T Cell Receptor Clone and Soluble Immune Checkpoint Proteins Associated with Clinical Outcomes Following Immune Checkpoint Inhibitor Treatment in Advanced Cancers.Frontiers in Immunology, vol. 12, Jun. 2021, doi:10.3389/fimmu.2021.649343.

Min, Qing, et al. “RAG1 Splicing Mutation Causes Enhanced B Cell Differentiation and Autoantibody Production.JCI Insight, vol 6, no. 19, Oct. 2021, doi:10.1172/jci.insight.148887.

Coelho, C.H., et al. “A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes.Nature Communications, vol. 12, Mar. 2021, doi: 10.1038/s41467-021-21955-1.

Amoriello, Roberta, et al. “TCR repertoire diversity in Multiple Sclerosis: High-dimensional bioinformatics analysis of sequences from brain, cerebrospinal fluid and peripheral blood.EBioMedicine, vol. 68, Jun. 2021, doi: 10.1016/j.ebiom.2021.103429.

Dasgupta, Suryasarathi, et al. “γδ T Cells Control Gut Pathology in a Chronic Inflammatory Model of Colorectal Cancer.Cellular and Molecular Gastroenterology and Hepatology, vol. 12, no. 3, Jan. 2021, p. 1163-1165, doi: 10.1016/j.jcmgh.2021.05.002.

Verhagen, Johan, et al. “Human CD4+ T cells specific for dominant epitopes of SARS-CoV-2 Spike and Nucleocapsid proteins with therapeutic potential.Clinical & Experimental Immunology, vol. 205, no. 3, Sept. 2021, p. 363-378, doi: 10.1111/cei.13627.

Mahajan, Vinay S., et al. “B1a and B2 cells are characterized by distinct CpG modification states at DNMT3A-maintained enhancers.Nature Communications, vol. 12, Apr. 2021, p. 1-17, doi: 10.1038/s41467-021-22458-9.

Goldberg, Rimma, et al. “A Crohn’s Disease-associated IL2RA Enhancer Variant Determines the Balance of T Cell Immunity by Regulating Responsiveness to IL-2 Signalling.Journal of Crohn’s and Colitis, vol. 15, no. 12, Dec. 2021, p. 2054-2065, doi: 10.1093/ecco-jcc/jjab103.

Liang, Hongling, et al. “TMB and TCR Are Correlated Indicators Predictive of the Efficacy of Neoadjuvant Chemotherapy in Breast Cancer. Frontiers in Oncology, vol. 11, Dec. 2021, doi:10.3389/fonc.2021.740427.

Yang, Yang, et al. “CTLA-4 expression by B-1a B cells is essential for immune tolerance.Nature Communications, vol. 12, Jan. 2021, p. 1-17, doi:10.1038/s41467-020-20874-x.

Baloche, Valentin, et al. “Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model.Scientific Reports, vol. 11, Mar. 2021, p. 1-18, doi:10.1038/s41467-020-20874-x.

Razzaghi, Raud, et al. “Compromised counterselection by FAS creates an aggressive subtype of germinal center lymphoma.Journal of Experimental Medicine, vol. 218, no. 3, Mar. 2021, doi:10.1084/jem.20201173.

Borowska, Marta T., et al. “The molecular characterization of antibody binding to a superantigen-like protein from a commensal microbe.Proceedings of the National Academy of Sciences, vol. 118, no. 39, Sept. 2021, doi:10.1073/pnas.2023898118.

Rice, Michael T., et al. “Recognition of the antigen-presenting molecule MR1 by a Vδ3+ γδ T cell receptor.Proceedings of the National Academy of Sciences, vol. 118, no. 49, Nov. 2021, doi:10.1073/pnas.2110288118.

2020

Amoriello, Roberta, et al. “The TCR Repertoire Reconstitution in Multiple Sclerosis: Comparing One-Shot and Continuous Immunosuppressive Therapies.” Frontiers in Immunology, vol. 11, Apr. 2020, doi:10.3389/fimmu.2020.00559.

Ekeke, Chigozirim N., et al. “Intrapleural Interleukin-2–Expressing Oncolytic Virotherapy Enhances Acute Antitumor Effects and T-Cell Receptor Diversity in Malignant Pleural Disease.” The Journal of Thoracic and Cardiovascular Surgery, Dec. 2020, doi:10.1016/j.jtcvs.2020.11.160.

Tang, Yunxia, et al. “TruNeo: An Integrated Pipeline Improves Personalized True Tumor Neoantigen Identification.” BMC Bioinformatics, vol. 21, no. 1, Dec. 2020, p. 532, doi:10.1186/s12859-020-03869-9.

Poran, Asaf, et al. “Combined TCR Repertoire Profiles and Blood Cell Phenotypes Predict Melanoma Patient Response to Personalized Neoantigen Therapy plus Anti-PD-1.” Cell Reports Medicine, vol. 1, no. 8, Nov. 2020, p. 100141, doi:10.1016/j.xcrm.2020.100141.

Choi, Da‑Won, et al. “Co‑transplantation of Tonsil‑derived Mesenchymal Stromal Cells in Bone Marrow Transplantation Promotes Thymus Regeneration and T Cell Diversity Following Cytotoxic Conditioning.” International Journal of Molecular Medicine, vol. 46, no. 3, June 2020, pp. 1166–74, doi:10.3892/ijmm.2020.4657.

Hoof, Ilka, et al. “Allergen-Specific IgG+ Memory B Cells Are Temporally Linked to IgE Memory Responses.” Journal of Allergy and Clinical Immunology, vol. 146, no. 1, July 2020, pp. 180–91, doi:10.1016/j.jaci.2019.11.046.

Coelho, Camila H., et al. “Antimalarial Antibody Repertoire Defined by Plasma IG Proteomics and Single B Cell IG Sequencing.” JCI Insight, vol. 5, no. 22, Nov. 2020, doi:10.1172/jci.insight.143471.

Ye, Xiaolan, et al. “High-Throughput Sequencing-Based Analysis of T Cell Repertoire in Lupus Nephritis.” Frontiers in Immunology, vol. 11, Aug. 2020, doi:10.3389/fimmu.2020.01618.

Boi, Shannon K., et al. “Obesity Diminishes Response to PD-1-Based Immunotherapies in Renal Cancer.” Journal for ImmunoTherapy of Cancer, vol. 8, no. 2, Dec. 2020, p. e000725, doi:10.1136/jitc-2020-000725.

Niu, Xuefeng, et al. “Longitudinal Analysis of T and B Cell Receptor Repertoire Transcripts Reveal Dynamic Immune Response in COVID-19 Patients.” Frontiers in Immunology, vol. 11, Sept. 2020, doi:10.3389/fimmu.2020.582010.

Stankovic, Sanda, et al. “Cytomegalovirus Replication Is Associated with Enrichment of Distinct Γδ T Cell Subsets Following Lung Transplantation: A Novel Therapeutic Approach?The Journal of Heart and Lung Transplantation, vol. 39, no. 11, Nov. 2020, pp. 1300–12, doi:10.1016/j.healun.2020.08.014.

Soloff, Adam C., et al. “HMGB1 Promotes Myeloid Egress and Limits Lymphatic Clearance of Malignant Pleural Effusions.” Frontiers in Immunology, vol. 11, Sept. 2020, doi:10.3389/fimmu.2020.02027.

Quayle, Steven N., et al. “CUE-101, a Novel E7-PHLA-IL2-Fc Fusion Protein, Enhances Tumor Antigen-Specific T-Cell Activation for the Treatment of HPV16-Driven Malignancies.” Clinical Cancer Research, vol. 26, no. 8, Apr. 2020, pp. 1953–64, doi:10.1158/1078-0432.CCR-19-3354.

Yang, Hong‐Ge, et al. “Transforming Growth Factor‐β Promotes the Function of HIV‐specific CXCR5 + CD8 T Cells.” Microbiology and Immunology, vol. 64, no. 6, June 2020, pp. 458–68, doi:10.1111/1348-0421.12789.

Djaoud, Zakia, and Peter Parham. “Dimorphism in the TCRγ-Chain Repertoire Defines 2 Types of Human Immunity to Epstein-Barr Virus.” Blood Advances, vol. 4, no. 7, Apr. 2020, pp. 1198–205, doi:10.1182/bloodadvances.2019001179.

Tune, Cornelia, et al. “Effects of Sleep on the Splenic Milieu in Mice and the T Cell Receptor Repertoire Recruited into a T Cell Dependent B Cell Response.” Brain, Behavior, & Immunity – Health, vol. 5, May 2020, p. 100082, doi:10.1016/j.bbih.2020.100082.

Prokop, Jeremy W., et al. “Virus-Induced Genetics Revealed by Multidimensional Precision Medicine Transcriptional Workflow Applicable to COVID-19.” Physiological Genomics, vol. 52, no. 6, June 2020, pp. 255–68, doi:10.1152/physiolgenomics.00045.2020.

Gastman, Brian, et al. “Defining Best Practices for Tissue Procurement in Immuno-Oncology Clinical Trials: Consensus Statement from the Society for Immunotherapy of Cancer Surgery Committee.” Journal for ImmunoTherapy of Cancer, vol. 8, no. 2, Nov. 2020, p. e001583, https://doi.org/10.1136/jitc-2020-001583.

Yeh, Tzu-Wen, et al. “APRIL-Dependent Lifelong Plasmacyte Maintenance and Immunoglobulin Production in Humans.” Journal of Allergy and Clinical Immunology, vol. 146, no. 5, Nov. 2020, pp. 1109-1120.e4, doi:10.1016/j.jaci.2020.03.025.

Zhang, Lu, et al. “Comprehensive Investigation of T and B Cell Receptor Repertoires in an MC38 Tumor Model Following Murine Anti‑PD‑1 Administration.” Molecular Medicine Reports, vol. 22, no. 2, May 2020, pp. 975–85, doi:10.3892/mmr.2020.11169.

Liao, Yu-Wen, et al. “Enterovirus 71 Infection Shapes Host T Cell Receptor Repertoire and Presumably Expands VP1-Specific TCRβ CDR3 Cluster.” Pathogens, vol. 9, no. 2, Feb. 2020, p. 121, doi:10.3390/pathogens9020121.

Mitchell, Angela M., and Aaron W. Michels. “T Cell Receptor Sequencing in Autoimmunity.” Journal of Life Sciences (Westlake Village, Calif.), vol. 2, no. 4, Dec. 2020, pp. 38–58, doi:10.36069/jols/20201203.

Ott, Patrick, et al. “A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer.” Cell, vol. 183, no. 2, Oct. 2020, doi: 10.1016/j.cell.2020.08.053.

2019

Chen, Hui, et al. “Profiling the Pattern of the Human T-Cell Receptor Γδ Complementary Determinant Region 3 Repertoire in Patients with Lung Carcinoma via High-Throughput Sequencing Analysis.Cellular & Molecular Immunology, vol. 16, no. 3, Mar. 2019, pp. 250–59, doi:10.1038/cmi.2017.157.

Yamashita, Motoi, et al. “A Synonymous Splice Site Mutation in IL2RG Gene Causes Late-Onset Combined Immunodeficiency.” International Journal of Hematology, vol. 109, no. 5, May 2019, pp. 603–11, doi:10.1007/s12185-019-02619-9.

Wu, Shang-Gin, et al. “High Throughput Sequencing of T-Cell Receptor Repertoire Using Dry Blood Spots.” Journal of Translational Medicine, vol. 17, no. 1, Dec. 2019, p. 47, doi:10.1186/s12967-019-1796-4.

Zhang, Jiajia, et al. Analysis of TCR β CDR3 Sequencing Data for Tracking Anti-Tumor Immunity. 2019, pp. 443–64, doi:10.1016/bs.mie.2019.08.006.

Konishi, Hiroki, et al. “Capturing the Differences between Humoral Immunity in the Normal and Tumor Environments from Repertoire-Seq of B-Cell Receptors Using Supervised Machine Learning.” BMC Bioinformatics, vol. 20, no. 1, Dec. 2019, p. 267, doi:10.1186/s12859-019-2853-y.

Fuchs, Tina, et al. “Immediate Neutrophil-Variable-T Cell Receptor Host Response in Bacterial Meningitis.Frontiers in Neurology, vol. 10, Apr. 2019, doi:10.3389/fneur.2019.00307.

Lee, Mijeong, et al. “Preferential Infiltration of Unique Vγ9Jγ2-Vδ2 T Cells Into Glioblastoma Multiforme.” Frontiers in Immunology, vol. 10, Mar. 2019, doi:10.3389/fimmu.2019.00555.

Rettig, Trisha A., et al. “A Comparison of Unamplified and Massively Multiplexed PCR Amplification for Murine Antibody Repertoire Sequencing.” FASEB BioAdvances, vol. 1, no. 1, Jan. 2019, pp. 6–17, doi:10.1096/fba.1017.

Strauli, Nicolas, et al. “The Genetic Interaction between HIV and the Antibody Repertoire.” BioRxiv, Jan. 2019, p. 646968, doi:10.1101/646968.

Geng, Zi-Han, et al. “Human Colorectal Cancer Cells Frequently Express IgG and Display Unique Ig Repertoire.” World Journal of Gastrointestinal Oncology, vol. 11, no. 3, Mar. 2019, pp. 195–207, doi:10.4251/wjgo.v11.i3.195.

McCaw, Tyler R., et al. “The Expression of MHC Class II Molecules on Murine Breast Tumors Delays T-Cell Exhaustion, Expands the T-Cell Repertoire, and Slows Tumor Growth.Cancer Immunology, Immunotherapy, vol. 68, no. 2, Feb. 2019, pp. 175–88, doi:10.1007/s00262-018-2262-5.

Chang, Che-Mai, et al. “Characterization of T-Cell Receptor Repertoire in Patients with Rheumatoid Arthritis Receiving Biologic Therapies.” Disease Markers, vol. 2019, July 2019, pp. 1–12, doi:10.1155/2019/2364943.

Kuo, Ho-Chang, et al. “Global Investigation of Immune Repertoire Suggests Kawasaki Disease Has Infectious Cause.” Circulation Journal, vol. 83, no. 10, Sept. 2019, pp. 2070–78, doi:10.1253/circj.CJ-19-0206.

Guo, Changlong, et al. “Deep Targeted Sequencing Reveals the Diversity of TRB-CDR3 Repertoire in Patients with Preeclampsia.” Human Immunology, vol. 80, no. 10, Oct. 2019, pp. 848–54, doi:10.1016/j.humimm.2019.04.003.

Li, Yuxia, et al. “Identification of the Ligands of TCRγδ by Screening the Immune Repertoire of ΓδT Cells From Patients With Tuberculosis.” Frontiers in Immunology, vol. 10, Sept. 2019, doi:10.3389/fimmu.2019.02282.

2018

Hunter, Stuart, et al. “Human Liver Infiltrating Γδ T Cells Are Composed of Clonally Expanded Circulating and Tissue-Resident Populations.” Journal of Hepatology, vol. 69, no. 3, Sept. 2018, pp. 654–65, doi:10.1016/j.jhep.2018.05.007.

Jiang, Qiong, et al. “Patient-Shared TCRβ-CDR3 Clonotypes Correlate with Favorable Prognosis in Chronic Hepatitis B.” European Journal of Immunology, vol. 48, no. 9, Sept. 2018, pp. 1539–49, doi:10.1002/eji.201747327.

Jiang, Qiong, et al. “Analysis of T Cell Receptor Repertoire in Monozygotic Twins Concordant and Discordant for Chronic Hepatitis B Infection.” Biochemical and Biophysical Research Communications, vol. 497, no. 1, Feb. 2018, pp. 153–59, doi:10.1016/j.bbrc.2018.02.043.

Huang, Weiqing, et al. “Belimumab Promotes Negative Selection of Activated Autoreactive B Cells in Systemic Lupus Erythematosus Patients.” JCI Insight, vol. 3, no. 17, Sept. 2018, doi:10.1172/jci.insight.122525.

Dickinson, Gregory S., et al. “IL-7 Enables Antibody Responses to Bacterial Polysaccharides by Promoting B Cell Receptor Diversity.” The Journal of Immunology, vol. 201, no. 4, Aug. 2018, pp. 1229–40, doi:10.4049/jimmunol.1800162.

Cheng, Chaofei, et al. “Next Generation Sequencing Reveals Changes of the Γδ T Cell Receptor Repertoires in Patients with Pulmonary Tuberculosis.” Scientific Reports, vol. 8, no. 1, Dec. 2018, p. 3956, doi:10.1038/s41598-018-22061-x.

Shukla, Girja S., et al. “Immunization with Tumor Neoantigens Displayed on T7 Phage Nanoparticles Elicits Plasma Antibody and Vaccine-Draining Lymph Node B Cell Responses.” Journal of Immunological Methods, vol. 460, Sept. 2018, pp. 51–62, doi:10.1016/j.jim.2018.06.009.

Fahl, Shawn P., et al. “Role of a Selecting Ligand in Shaping the Murine Γδ-TCR Repertoire.” Proceedings of the National Academy of Sciences, vol. 115, no. 8, Feb. 2018, pp. 1889–94, doi:10.1073/pnas.1718328115.

Zhang, Chenchen, et al. “Impact of a 3-Months Vegetarian Diet on the Gut Microbiota and Immune Repertoire.” Frontiers in Immunology, vol. 9, Apr. 2018, doi:10.3389/fimmu.2018.00908.

Textor, Johannes, et al. “Deep Sequencing Reveals Transient Segregation of T Cell Repertoires in Splenic T Cell Zones during an Immune Response.The Journal of Immunology, vol. 201, no. 2, July 2018, pp. 350–58, doi:10.4049/jimmunol.1800091.

Fähnrich, Anke, et al. “CD154 Costimulation Shifts the Local T-Cell Receptor Repertoire Not Only During Thymic Selection but Also During Peripheral T-Dependent Humoral Immune Responses.” Frontiers in Immunology, vol. 9, May 2018, doi:10.3389/fimmu.2018.01019.

Tedesco, Dana, et al. “Alterations in Intestinal Microbiota Lead to Production of Interleukin 17 by Intrahepatic Γδ T-Cell Receptor–Positive Cells and Pathogenesis of Cholestatic Liver Disease.” Gastroenterology, vol. 154, no. 8, June 2018, pp. 2178–93, doi:10.1053/j.gastro.2018.02.019.

Davey, Martin S., et al. “The Human Vδ2+ T-Cell Compartment Comprises Distinct Innate-like Vγ9+ and Adaptive Vγ9- Subsets.” Nature Communications, vol. 9, no. 1, Dec. 2018, p. 1760, doi:10.1038/s41467-018-04076-0.

Davey, Martin S., et al. “Recasting Human Vδ1 Lymphocytes in an Adaptive Role.” Trends in Immunology, vol. 39, no. 6, June 2018, pp. 446–59, doi:10.1016/j.it.2018.03.003.

McCaw, Tyler R., et al. “The Expression of Class II Major Histocompatibility Molecules on Breast Tumors Delays T Cell Exhaustion, Expands the T Cell Repertoire and Slows Tumor Growth.” BioRxiv, Apr. 2018, p. 294124, doi:10.1101/294124.

Wu, J., et al. “Expanded TCRβ CDR3 Clonotypes Distinguish Crohn’s Disease and Ulcerative Colitis Patients.” Mucosal Immunology, vol. 11, no. 5, Sept. 2018, pp. 1487–95, doi:10.1038/s41385-018-0046-z.

Spence, Allyson, et al. “Revealing the Specificity of Regulatory T Cells in Murine Autoimmune Diabetes.” Proceedings of the National Academy of Sciences, vol. 115, no. 20, May 2018, pp. 5265–70, doi:10.1073/pnas.1715590115.

2017

Mitchell, Angela M., et al. “Shared Αβ TCR Usage in Lungs of Sarcoidosis Patients with Löfgren’s Syndrome.” The Journal of Immunology, vol. 199, no. 7, Oct. 2017, pp. 2279–90, doi:10.4049/jimmunol.1700570.

Ritvo, Paul-Gydéon, et al. “High-Resolution Repertoire Analysis of Tfr and Tfh Cells Reveals Unexpectedly High Diversities Indicating a Bystander Activation of Follicular T Cells.” BioRxiv, Dec. 2017, p. 231977, https://doi.org/10.1101/231977.

Probst, Philipp, et al. “Sarcoma Eradication by Doxorubicin and Targeted TNF Relies upon CD8 + T-Cell Recognition of a Retroviral Antigen.” Cancer Research, vol. 77, no. 13, July 2017, pp. 3644–54, doi:10.1158/0008-5472.CAN-16-2946.

Katoh, Hiroto, et al. “Immunogenetic Profiling for Gastric Cancers Identifies Sulfated Glycosaminoglycans as Major and Functional B Cell Antigens in Human Malignancies.” Cell Reports, vol. 20, no. 5, Aug. 2017, pp. 1073–87, doi:10.1016/j.celrep.2017.07.016.

Chen, Hui, et al. “Characterization of the Diversity of T Cell Receptor Γδ Complementary Determinant Region 3 in Human Peripheral Blood by Immune Repertoire Sequencing.” Journal of Immunological Methods, vol. 443, Apr. 2017, pp. 9–17, doi:10.1016/j.jim.2017.01.009.

Davey, Martin S., et al. “Clonal Selection in the Human Vδ1 T Cell Repertoire Indicates Γδ TCR-Dependent Adaptive Immune Surveillance.” Nature Communications, vol. 8, no. 1, Apr. 2017, p. 14760, doi:10.1038/ncomms14760.

Barisa, M., et al. “E. Coli Promotes Human Vγ9Vδ2 T Cell Transition from Cytokine-Producing Bactericidal Effectors to Professional Phagocytic Killers in a TCR-Dependent Manner.Scientific Reports, vol. 7, no. 1, Dec. 2017, p. 2805, doi:10.1038/s41598-017-02886-8.

Okano, Tsubasa, et al. “Maternal T and B Cell Engraftment in Two Cases of X-Linked Severe Combined Immunodeficiency with IgG1 Gammopathy.” Clinical Immunology, vol. 183, Oct. 2017, pp. 112–20, doi:10.1016/j.clim.2017.08.003.

Wong, Henry Sung-Ching, et al. “V-J Combinations of T-Cell Receptor Predict Responses to Erythropoietin in End-Stage Renal Disease Patients.” Journal of Biomedical Science, vol. 24, no. 1, Dec. 2017, p. 43, doi:10.1186/s12929-017-0349-5.

2016

Hou, Dongni, et al. “Immune Repertoire Diversity Correlated with Mortality in Avian Influenza A (H7N9) Virus Infected Patients.Scientific Reports, vol. 6, no. 1, Dec. 2016, p. 33843, https://doi.org/10.1038/srep33843.

Al-Hussaini, Muneera, et al. “Targeting CD123 in Acute Myeloid Leukemia Using a T-Cell–Directed Dual-Affinity Retargeting Platform.” Blood, vol. 127, no. 1, Jan. 2016, pp. 122–31, doi:10.1182/blood-2014-05-575704.

Sims, Jennifer S., et al. “Diversity and Divergence of the Glioma-Infiltrating T-Cell Receptor Repertoire.” Proceedings of the National Academy of Sciences, vol. 113, no. 25, June 2016, pp. E3529–37, https://doi.org/10.1073/pnas.1601012113.

Lee, Y. N., et al. “Characterization of T and B Cell Repertoire Diversity in Patients with RAG Deficiency.” Science Immunology, vol. 1, no. 6, Dec. 2016, pp. eaah6109–eaah6109, doi:10.1126/sciimmunol.aah6109.

2015

Byrne-Steele, Miranda, et al. “iRock 2.0 and the iR-Processor: An Automated Immune Repertoire Library Preparation Platform for NGS (TECH2P.919).” The Journal of Immunology, vol. 194, no. 1 Supplement, May 2015, pp. 206.29–206.29, https://www.jimmunol.org/content/194/1_Supplement/206.29.

Yang, Yang, et al. “Distinct Mechanisms Define Murine B Cell Lineage Immunoglobulin Heavy Chain (IgH) Repertoires.” ELife, vol. 4, Sept. 2015, doi:10.7554/eLife.09083.

Zhao, Tongbiao, et al. “Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells.” Cell Stem Cell, vol. 17, no. 3, Sept. 2015, pp. 353–59, https://doi.org/10.1016/j.stem.2015.07.021.

2014

Byrne-Steele, Miranda, et al. “Automation of Immune Repertoire Amplification on the iC-Processor (TECH1P.851).” The Journal of Immunology, vol. 192, no. 1 Supplement, May 2014, pp. 69.19–69.19, https://www.jimmunol.org/content/192/1_Supplement/69.19.

Lee, Yu Nee, et al. “A Systematic Analysis of Recombination Activity and Genotype-Phenotype Correlation in Human Recombination-Activating Gene 1 Deficiency.” Journal of Allergy and Clinical Immunology, vol. 133, no. 4, Apr. 2014, pp. 1099-1108.e12, doi:10.1016/j.jaci.2013.10.007.

Sims, J., et al. “IT-32 Divergence of Intratumoral and Systemic T Cell Repertoires Reflects Local Monocyte Profiles During Glioma Progression.” Neuro-Oncology, vol. 16, no. suppl 5, Nov. 2014, pp. v116–17, doi:10.1093/neuonc/nou258.30.

Sims, Jennifer, et al. “TCR Repertoire Divergence Reflects Micro-Environmental Immune Phenotypes in Glioma.” Journal for ImmunoTherapy of Cancer, vol. 2, no. S3, Dec. 2014, p. O19, doi:10.1186/2051-1426-2-S3-O19.

Alleyne, Jessica, et al. “Biomarker: Long Term Study of Breast Cancer Specific CDR3s in Peripheral Blood (TUM2P.894).” The Journal of Immunology, vol. 192, no. 1 Supplement, May 2014, pp. 71.18–71.18, https://www.jimmunol.org/content/192/1_Supplement/71.18.

Wang, Chunlin, et al. “Breast Cancer Diagnosis by High Throughput Sequencing of T Cell Receptors from Peripheral Blood Samples (TUM2P.905).” The Journal of Immunology, vol. 192, no. 1 Supplement, May 2014, pp. 71.29–71.29, https://www.jimmunol.org/content/192/1_Supplement/71.29.

O’Connell, Amy E., et al. “Next Generation Sequencing Reveals Skewing of the T and B Cell Receptor Repertoires in Patients with Wiskott–Aldrich Syndrome.” Frontiers in Immunology, vol. 5, July 2014, doi:10.3389/fimmu.2014.00340.

2013

Han, Jian, et al. “R10K Update: NGS of Immune Repertoire for Biomarker Discoveries (P3241).” The Journal of Immunology, vol. 190, no. 1 Supplement, May 2013, pp. 192.6–192.6, https://www.jimmunol.org/content/190/1_Supplement/192.6.

Sims, Jennifer S., et al. “Tumor-Associated T Cell Receptor Repertoires in Low- and High-Grade Gliomas.” Journal for ImmunoTherapy of Cancer, vol. 1, no. S1, Nov. 2013, p. P143, http://dx.doi.org/10.1186/2051-1426-1-S1-P143.

2012

Han, Jian, et al. “R10K: An International Collaborative Project for Biomarker Discovery (58.7).” The Journal of Immunology, vol. 188, no. 1 Supplement, May 2012, pp. 58.7–58.7, https://www.jimmunol.org/content/188/1_Supplement/58.7.

Wang, Chunlin, et al. “Evaluation of Three next Generation Sequencing Platforms for Immune Repertoire Sequencing (58.10).” The Journal of Immunology, vol. 188, no. 1 Supplement, May 2012, pp. 58.10–58.10, https://www.jimmunol.org/content/188/1_Supplement/58.10.

Han, Jian, et al. “Identification and Temporal Monitoring of Breast Cancer-Associated T Cell Receptors with High Throughput Sequencing (46.23).” The Journal of Immunology, vol. 188, no. 1 Supplement, May 2012, pp. 46.23–46.23, https://www.jimmunol.org/content/188/1_Supplement/46.23.

Peaudecerf, Laetitia, et al. “Thymocytes May Persist and Differentiate without Any Input from Bone Marrow Progenitors.” Journal of Experimental Medicine, vol. 209, no. 8, July 2012, pp. 1401–08, doi:10.1084/jem.20120845.

2011

Byrne-Steele, Miranda, et al. “Development of an Alternative Method for the Identification and Production of Antigen-Specific Monoclonal Antibodies (65.16).” The Journal of Immunology, vol. 186, no. 1 Supplement, Apr. 2011, pp. 65.16–65.16, https://www.jimmunol.org/content/186/1_Supplement/65.16.

Han, Jian, et al. “Profiling the Pattern of Human Immunoglobulin SHM and CSR in B Memory Cells via High-Throughput Sequencing (62.11).” The Journal of Immunology, vol. 186, no. 1 Supplement, Apr. 2011, pp. 62.11–62.11, https://www.jimmunol.org/content/186/1_Supplement/62.11

Wang, Chunlin, et al. “Immune Repertoire High-Throughput Sequence Analysis (IRAS) Web Service (65.20).” The Journal of Immunology, vol. 186, no. 1 Supplement, Apr. 2011, p. 65.20, https://www.jimmunol.org/content/186/1_Supplement/65.20.

2010

Wang, C., et al. “High Throughput Sequencing Reveals a Complex Pattern of Dynamic Interrelationships among Human T Cell Subsets.” Proceedings of the National Academy of Sciences, vol. 107, no. 4, Jan. 2010, pp. 1518–23, doi:10.1073/pnas.0913939107.