Advance your clinical development and drug discovery program with RepSeq+

Capture clonality and diversity data of all seven chains in a single reaction

Understanding the diversity of the adaptive immune repertoire is critical for advancing disease biomarker discovery and therapeutic development. However, current methodologies to study T and B cell receptor sequences are limited by low sensitivity, inclusiveness, and throughput. Therefore, we developed RepSeq+, a sensitive, quantitative, and high-throughput assay that combines multiplex PCR with NGS to analyze all seven chains of the adaptive immune system in a single reaction.

RepSeq+

All-in-one solution for adaptive immune repertoire analysis

With high sensitivity, we uncover rare clonotypes, crucial for understanding immune responses and disease mechanisms.

By analyzing all 7 chains of B-cell and T-cell receptors, our approach offers a comprehensive view of immune cell diversity, capturing various clonotypes and subpopulations.

Our technique delivers results free from bias, ensuring accurate representation of immune cell diversity.

Our analysis provides precise quantification of immune cell populations, allowing for accurate assessment and comparison.

Our methods ensure consistent and reliable results across experiments, enabling confidence in data reproducibility and reliability.

Our approach delivers error-free results, guaranteeing accurate and reliable sequencing data.

Looking for rare clones in a single chain? RepSeq might be for you

RepSeq+

All-in-one solution for adaptive immune repertoire analysis

Sensitive
With high sensitivity, we uncover rare clonotypes, crucical for understanding immune responses and disease mechanisms.
Comprehensive
By analyzing all 7 chains of B-cell and T-cell receptors, our approach offers a comprehensive view of immune cell diversity, capturing various clonotypes and subpopulations.
Unbiased
Our technique delivers results free from bias, ensuring accurate representation of immune cell diversity.
Quantitative
Our analysis provides precise quantification of immune cell populations, allowing for accurate assessment and comparison.
Reproducible
Our methods ensure consistent and reliable results across experiments, enabling confidence in data reproducibility and reliability.
Accurate
Our approach delivers error-free results, guaranteeing accurate and reliable sequencing data.

Looking for rare clones in a single chain? RepSeq might be for you

Turn data into actionable insights

Simplify complex repertoire dynamics with colorful data outputs:

  • Tree maps visualize both chain diversity and clonality
  • B-cell network plots go beyond simple clonal expansion
  • Longitudinal tracking of dominant or expanding clones

RepSeq+ in Action

Case study: Immune Repertoire Sequencing for Pre- and Post-Treatment Monitoring in Cancer

Case study: Immune Repertoire Sequencing for Pre- and Post-Treatment Monitoring in Cancer

Renal cell carcinoma poster

Autoimmune case study

Autoimmune case study

Ready to Take Your Immunological Discoveries to the Next Level?