Next generation immune sequencing for infectious disease

Uncover the drivers of infectious disease progression and recovery

Bulk Repertoire Sequencing

Data from examining the immune repertoire of cancer patients can be used to identify patterns associated with positive outcomes and monitor the progress of immunotherapies in clinical trials. Single cell immune sequencing technologies provide an even more granular view of individual T cell or B cell populations following immunotherapy, providing unprecedented detail for informing cancer treatment.

Single cell immune sequencing

Data from examining the immune repertoire of cancer patients can be used to identify patterns associated with positive outcomes and monitor the progress of immunotherapies in clinical trials. Single cell immune sequencing technologies provide an even more granular view of individual T cell or B cell populations following immunotherapy, providing unprecedented detail for informing cancer treatment.

Explore how you can use these technologies in the case studies and webinar below

prognostic_indicators

Discover prognostic indicators

  • Track changes from symptom onset through recovery in all seven chains of the immune repertoire
  • Explore correlations between chain type switching and recovery
  • Identify potent biomarkers for predicting disease progression
neutralizing antibodies@2x

Capture rare neutralizing antibodies

  • Maintain cognate pairing of heavy and light chains with single cell immune sequencing
  • Conserve rare clonotypes throughout library preparation
  • Pull out antigen-specific antibodies from patient populations
immune response@2x

Identify patient specific immune responses

  • Investigate shared and unique clonality signatures
  • Identify signatures of virus-induced chronic immune issues
  • Combine with total RNA sequencing to identify gene pathways, organ damage, and immune response

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