Learn with us

Learn more about immune biology, repertoire sequencing, and iRepertoire’s solutions for characterizing immune diversity.

Click a topic to see what articles are available:

Immunology basics
T-and-B-cell-graphic-01

T cell and B cell Overview

BCR-germline-V8

Diversity and differentiation in the adaptive immune system

CDR3-distribution-graphic-1

The immune repertoire and adaptome

NGS basics
Sequencing-Workflow-1

NGS overview: from sample to sequencer to results

NGS sequencing coverage process

NGS considerations: coverage, read length, multiplexing

iRepertoire: Immunology meets NGS
T-and-B-cell-graphic-01

T cell and B cell Overview

BCR-germline-V8

Diversity and differentiation in the adaptive immune system

CDR3-distribution-graphic-1

The immune repertoire and adaptome

Project planning, sample preparation and submission
pcr strip and biological microscope

Choice of starting template: RNA vs gDNA vs cDNA

MiSeq_2

Choosing your read depth

DNA samples are loaded to 96-well plate for PCR analysis

Pooling samples

graphic of cancer cell, shown in orange, and lymphocytes, shown around the cancer cell in blue

Cell-sorting guide

sample-prep-graphics-01-2

Blood collection and sample considerations

rosebox-BFdSCxmqvYc-unsplash

Shipping samples, receiving products, and submitting data

Pipette_tube_in_hood

Sample submission guide – bulk repertoire

Publications, posters, and patents
iRepertoire poster entitled iR-HLA cassette: An automated and integrated solution for NGS based HLA-typing

Posters

Experienced businesswoman reading publication via laptop computer making research for planning startup at desktop,female secretary checking mail on netbook organizing working process in office

Publications and patents