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Researchers at the Pittsburgh School of Medicine used a combination of RNA-seq and targeted immune sequencing to link a protein overexpressed within MPEs to reduced levels of T cell receptor (TCR) diversity

Finding new therapeutic targets in cancer research through changes in the immune adaptome

Nov 2, 2020

iPair automation in the clinical laboratory. Pipetting robot laboratory. Medicine robotics. NGS DNA diagnostics. Research and science background

Cue Biopharma uses iPair technology to demonstrate efficacy of Tumor Antigen-Specific T-Cell activating drug

Oct 29, 2020

Figure 3 Longitudinal analysis of TCR and BCR repertoires of four individuals. Samples were collected from three patients from early-mid stages after symptom onset (days 3, 5, 7, 12, 14) to the convalescent stage (days 17, 19). Samples from a healthy seasonal quadrivalent influenza vaccinee before and after vaccination (days 0, 4, 14, and 28) were used as a control. (A) The proportion of TCR-TRA, -TRB, -TRD, -TRG and BCR-IgH, -IgK, -IgL in the adaptive immune reservoirs. (B) Treemap plots representing unique CDR3 clonotypes in each of the seven chains on the indicated time points after symptom onset. The seven treemap plots each represent TCR-beta, -alpha, -delta, -gamma, and BCR-IgH, -IgK, -IgL. A rectangle in a treemap plot represents a unique clonotype. The size of a rectangle denotes the relative frequency of an individual CDR3 sequence, and the varying square size reflects areas of clonal expansion within the immune repertoire sampled. The color of the individual CDR3 sequence in each Treemap plot was randomly chosen, and thus, the colors do not precisely match between individual plots. From the left upper plot clockwise to the bottom plots: IgH, IgK, IgL, TRB, TRA, TRD, and TRG.

Scientists who discovered SARS just revealed a radar map of the immune system’s response to COVID-19

Oct 19, 2020

Translational Dx Virtual Summit

Translational Dx: Advances in Multi-Omic Oncology

Sep 9, 2020

Dr. Jian Han stands facing the camera in a polished white shirt, slightly smiled. Slightly blurred for the background is the view of an empty lab room at Hudson Alpha Institute for Biotechnology

Presentation from our Founder, Dr. Jian Han

Aug 31, 2020

Beckman Coulter COVID-19 Research Symposium

COVID-19 Research Symposium: Webinar

Jun 25, 2020

Launch of new viral RNA extraction solution with Beckman Coulter Life Sciences

May 18, 2020

New office on the HudsonAlpha campus

Screening local COVID-19 patient samples for antibodies

Apr 29, 2020

COVID-19 Science Spotlight on iRepertoire

Sharing COVID-19 updates: Science Spotlight

Apr 22, 2020

Rocket city scientists help in the fight against Coronavirus

Jan 31, 2020

SARS-CoV-2 virus medical illustration

Precision medicine workflow featuring RepSeq+ could help predict organ failure in COVID-19 patients

Jun 29, 2020

COVID-19 response: research and testing

Mar 19, 2020

Watch the Labroots webinar

Webinar: Immune system NGS from single cell to bulk RNA

Mar 1, 2020

iRep CEO Dennis Grimaud

Meet our new CEO

Feb 23, 2020

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